Production of N-acetylisopenicillin N and isopenicillin N from Streptomyces tokunonensis sp. nov.
نویسندگان
چکیده
N-Acetylisopenicillin N was isolated from the culture broth of Streptomyces tokunonensis sp. nov., and identified from 1H NMR spectroscopy and release of L-alpha-aminoadipic acid by acid hydrolysis. In the course of this study, the specimen of penicillin N isolated from this strain was proved to contain a small amount of isopenicillin N by HPLC.
منابع مشابه
Cloning and expression in Escherichia coli of isopenicillin N synthetase genes from Streptomyces lipmanii and Aspergillus nidulans.
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ورودعنوان ژورنال:
- The Journal of antibiotics
دوره 35 12 شماره
صفحات -
تاریخ انتشار 1982